G. Kim Prisk, Ph.D., D.Sc.

G. Kim Prisk, Ph.D., D.Sc.

Professor

UCSD Departments of Medicine and Radiology
9500 Gilman Dr., 0852
La Jolla, CA 92093-0852

Email: kprisk@ucsd.edu

Radiology Link: G. K. Prisk

Education

1977 Physics, University of Canterbury, New Zealand B.Sc.(Hons)
1979 Ionospheric Physics, University of Canterbury, New Zealand M.Sc.
1983 Pulmonary Physiology, University of Otago, New Zealand Ph.D.
2003 Pulmonary Physiology, University of Otago, New Zealand D.Sc.

Research & Professional Experience

1980 - 83 Scientific Officer, Department of Respiratory Medicine, Canterbury Hospital Board, Christchurch, NZ.
1983 - 85 Post Graduate Research Physiologist, Section of Physiology, Department of Medicine, UC San Diego
1985 - 93 Assistant Research Physiologist, Section of Physiology, Department of Medicine, UC San Diego
1993 - 95 Associate Research Physiologist, Section of Physiology, Department of Medicine, UC San Diego
1995 - 99 Associate Adjunct Professor, Division of Physiology, Department of Medicine, UC San Diego
1999 - Professor, Division of Physiology, Department of Medicine, UC San Diego
2006 - Professor, Department of Radiology, UC San Diego
2011 - Associate Editor, Journal of Applied Physiology

Honors & Awards

1979 Medical Research Council of New Zealand: Postgraduate Scholarship.
1991 NASA Group Achievement Award.
1994 NASA Group Achievement Award.
1997 Space Act Award.
2005 Elected Fellow - American Institute of Medical and Biological Engineering - AIMBE.
2007 Elected Senior Member - Institute of Electric and Electronic Engineers - IEEE.
2007 Honorary Member, Australian and New Zealand Society of Respiratory Scientists.

Research Focus

The scientific focus of my research career has been the understanding of the effects of gravity on the lung. This has developed into three overlapping areas of scientific investigation.

Direct studies of the effects of gravity on the lung.
This work has been the central focus of most of my career. The lung is greatly influenced by gravity, and so direct studies performed in the absence of gravity provide an ideal means to investigate this. I have been directly involved in almost all of the studies of lung function performed in space since the Shuttle began flying. These have included studies on SLS-1 (STS-40), SLS-2 (STS-58), LMS (STS-78) and Neurolab (STS-90) in which our team was the primary experimenter, and studies on D-2 (STS-55), ST-95 and STS-107 on which we were co-investigators.

Aerosol transport in the lung and the influence of gravity.
The second focus has been that of understanding aerosol transport in the lung, and the influence of gravity on these processes. As gravitational sedimentation plays critical role in the deposition of small and medium sized particles, studies in reduced gravity provide a means of probing these effects. These studies, first begun in 1995 have exclusively used the NASA Reduced Gravity Aircraft to provide short periods of reduced gravity experimental time, which are well-suited to theses studies. More recently, the increased interest in the problems associated with lunar dust in a reduced gravity environment (1/6G) have resulted in an expansion of these studies.

Quantitative MRI of the lung.
My most recent focus is that of using MRI to make quantitative functional measurements in the human lung of blood flow. MRI is traditionally not used in the lung because of low proton density and magnetic susceptibility artifacts. My colleagues and I have pioneered this new approach to lung imaging, free of radiation dose and so ideally suited to physiological studies, and this imaging modality is now being utilized in our studies pertaining to the development and effects of pulmonary interstitial edema.

Research Projects

Clearance of particles depositing the human lung in low gravity.
National Space Biomedical Research Institute
The major goal of this work is to measure the rate of clearance of deposited particles in the human lung when their deposition occurs during low-gravity.

Spatial-temporal dynamics of blood flow in the normal human lung.
National Heart Lung and Blood Institute
The major goal of this project is to characterize the spatial and temporal nature of variations in pulmonary blood flow in humans.

Three dimensional ballstocradiography in microgravity.
National Space Biomedical Research Institute


The major goal of this work is to perform 3-D ballistocardiography measurements in sustained microgravity on board the International Space Station to determine the nature of the signals and their utility when they are measured without the constraints imposed by gravity.

Other Recent and Current Studies:

Aerosol deposition in the lung in fractional gravity: Risk mitigation for Lunar and Martian habitats Effect of pulmonary interstitial edema on gas exchange.
Chantal Darquenne: Modeling of aerosol transport in alveolated airways
Susan R. Hopkins: Lung perfusion heterogeneity and mechanisms of edema
David Dubowitz: Cerebral response to sustained hypoxia
Chantal Darquenne: Quantitative MRI-based assessment of aerosol deposition in the lung

Selected Publications

(For a complete list plus links to abstracts and text of lab publications, please see the Physiology/NASA Lab Publications page)
  1. Bates, J.H.T., G.K. Prisk, T.E. Tanner and A.E. McKinnon. Correcting for the dynamic response of a respiratory mass spectrometer. Journal of Applied Physiology: Respiration Environmental and Exercise Physiology. 55(3): 1015-1022, 1983.
  2. Bates, J.H.T., G.K. Prisk, T.E. Tanner and A.E. McKinnon. Characterizing and correcting for the dynamic response of a bag-in-box system. Journal of Applied Physiology: Respiration Environmental and Exercise Physiology. 56(1): 254-258, 1984.
  3. Prisk, G.K., and A.E. McKinnon. A modelling approach to the estimation of CO diffusing capacity. J. Appl. Physiol. 62(1): 373-380, 1987.
  4. Prisk, G.K. and A.E. McKinnon. Estimation of the amount of stationary pulmonary blood from carbon monoxide uptake measurements. J. Appl. Physiol. 63(3): 1303-1308, 1987.
  5. Davis, F.M., M.P. Graves, H.J.B. Guy, G.K. Prisk and T.E. Tanner. Carbon dioxide response and breath-hold times in underwater hockey players. Undersea Biomed. Res. 14(6): 527-534, 1987.
  6. Tomioka, S., S. Kubo, H.J.B. Guy, and G.K. Prisk. Influence of collateral ventilation on single-breath washout curves. J. Appl. Physiol. 64(1): 429-434, 1988.
  7. Tomioka, Shinichi, Susumo Kubo, Harold J.B.Guy, and G.K. Prisk. Gravitational independence of single breath washout tests in recumbent dogs. J. Appl. Physiol. 64(2): 642-648, 1988.
  8. Guy, H.J., G.K. Prisk and J.B. West. Pulmonary function in microgravity: Spacelab 4 and beyond. Acta Astronautica 17(10): 1139-1143, 1988.
  9. Guy, H.J.B., G.K. Prisk, A.R. Elliott, and J.B. West. Maximum expiratory flow-volume curves during short periods of microgravity. J. Appl. Physiol. 70(6): 2587-2596, 1991
  10. Hempleman, S.C., F. L. Powell, and G.K. Prisk. Avian arterial chemoreceptor responses to steps of CO2 and O2. Respir. Physiol. 90:325-340, 1992.
  11. Prisk, G.K., H.J.B. Guy, A.R. Elliott, R.A. Deutschman III, and J.B. West. Pulmonary diffusing capacity, capillary blood volume and cardiac output during sustained microgravity. J. Appl. Physiol., 75:15-26, 1993.
  12. Guy, H.J.B., G.K. Prisk, A.R. Elliott, R.A. Deutschman III, and J.B. West. Inhomogeneity of pulmonary ventilation during sustained microgravity as determined by single-breath washouts. J. Appl. Physiol., 76: 1719-1729, 1994.
  13. Prisk, G.K., H.J.B. Guy, A.R. Elliott, and J.B. West. Inhomogeneity of pulmonary perfusion during sustained microgravity on Spacelab SLS-1. J. Appl. Physiol., 76: 1730-1738, 1994.
  14. Elliott, A.R. G.K. Prisk, H.J.B. Guy, and J.B. West. Lung volumes during sustained microgravity on Spacelab SLS-1. J. Appl. Physiol., 77:2005-2014, 1994.
  15. Prisk, G.K., H.J.B. Guy, A.R. Elliott, M. Paiva, and J.B. West. Ventilatory inhomogeneity determined from multiple breath washouts during sustained microgravity. J. Appl. Physiol. 78:597-607, 1995.
  16. Prisk, G.K., A.R. Elliott, H.J.B. Guy, J.M. Kosonen, and J.B. West. Pulmonary gas exchange and its determinants during sustained microgravity on Spacelabs SLS-1 and SLS-2. J. Appl. Physiol. 79: 1290-1298, 1995.
  17. Prisk, G.K., A.-M. Lauzon, S. Verbanck, A.R. Elliott, H.J.B. Guy, M. Paiva, and J.B. West. Anomalous behavior of helium and sulfur hexaflouride during single-breath tests in sustained microgravity. J. Appl. Physiol. 80:1126-1132, 1996.
  18. Verbanck, S., D. Linnarsson, G.K. Prisk, and M. Paiva. Specific ventilation distribution in microgravity. J. Appl. Physiol. 80:1458-1465, 1996.
  19. West, J.B., H.J.B. Guy, A.R. Elliott, and G.K. Prisk. Respiratory system in microgravity. The Handbook of Physiology Section 4: Environmental Physiology. M.J. Fregly and C.M. Blatteis (eds). New York, Oxford University Press. pp. 675-689, 1996.
  20. Elliott, A.R., G.K. Prisk, H.J.B. Guy, J. M. Kosonen, and J.B. West. Forced expirations and maximum expiratory flow-volume curves during sustained microgravity on SLS-1. J. Appl. Physiol., 81:33-43, 1996.
  21. Lauzon, A.-M., G.K. Prisk, A.R. Elliott, S. Verbanck, M. Paiva, and J.B. West. Paradoxical helium and sulfur hexafluoride single-breath washouts in short-term vs. sustained microgravity. J. Appl. Physiol. 82:859-865, 1997.
  22. West, J.B., A.R. Elliott, H.J.B. Guy, and G. K. Prisk. Pulmonary function in space. J. Am. Med. Assoc. 277:1957-1961, 1997.
  23. Verbanck, S., H. Larsson, D. Linnarsson, G.K. Prisk, J.B. West, and M. Paiva. Pulmonary tissue volume, cardiac output, and diffusing capacity in sustained microgravity. J. Appl. Physiol. 83:810-816, 1997.
  24. Darquenne, C., M. Paiva, J.B. West and G.K. Prisk. Effect of microgravity and hypergravity on deposition of 0.5 to 3 mm-diameter aerosol in the human lung. J. Appl. Physiol. 83:2029-2036, 1997.
  25. Prisk, G.K. , A.R. Elliott, H.J.B. Guy, S. Verbanck, M. Paiva, and J.B. West. Multiple-breath washin of helium and sulfur hexafluoride in sustained microgravity. J. Appl. Physiol. 84:244-252, 1998.
  26. Lauzon, A.-M., A.R. Elliott, M. Paiva, J.B. West and G.K. Prisk. Cardiogenic oscillation phase relationships during single-breath tests performed in microgravity. J. Appl. Physiol. 84:661-668, 1998.
  27. Elliott, A.R., G. K. Prisk, C. Schöllmann, and U. Hoffmann. Part Two: Hypercapnic ventilatory response in humans before, during and after 23 days of low level CO2 exposure. Aviat. Space Environ. Med., 69:391-396, 1998.
  28. Wantier, M., M. Estenne, S. Verbanck. G.K. Prisk, and M. Paiva. Chest wall mechanics in sustained microgravity. J. Appl. Physiol. 84:2060-2065, 1998.
  29. Darquenne, C., J.B. West, and G.K. Prisk. Deposition and dispersion of 1 mm aerosol boluses in the human lung: Effect of micro- and hypergravity. J. Appl. Physiol. 85:1252-1259, 1998.
  30. Darquenne, C., J.B. West, and G.K. Prisk. Dispersion of 0.5-2-mm aerosol in mG and hypergravity as a probe of convective inhomogeneity in the lung. J. Appl. Physiol. 86:1402-1409, 1999.
  31. Verbanck, S., C. Darquenne, G.K. Prisk, W. Vincken, and M. Paiva. A source of experimental underestimation of aerosol bolus deposition. J. Appl. Physiol. 86:1067-1074, 1999.
  32. Dutrieue, B., A.-M. Lauzon, S. Verbanck, A.R. Elliott, J.B. West, M. Paiva, and G.K. Prisk. Helium and sulfur hexafluoride bolus washin in short-term microgravity. J. Appl. Physiol. 85:1594-1602, 1999.
  33. Prisk, G.K., A.R. Elliott, and J.B. West. Sustained microgravity reduces the human ventilatory response to hypoxia but not hypercapnia. J. Appl. Physiol. 88:1421-1430, 2000.
  34. Prisk, G.K. Invited review: Microgravity and the lung. J. Appl. Physiol. 89: 385-396, 2000.
  35. Darquenne, C., M. Paiva, and G. K. Prisk. Effect of gravity on aerosol dispersion and deposition in the human lung after periods of breath-holding. J.Appl. Physiol. 89: 1787-1792, 2000.
  36. McElroy, M., A. Gerard, F.L. Powell, G.K. Prisk, N. Sentse, S. Holverda and J.B. West. Nocturnal O2 enrichment of room air at high altitude increases daytime O2 Saturation without changing control of ventilation. High Altitude Med and Biol. 1: 197-206, 2000.
  37. Y. Verbandt, M. Wantier, G. K. Prisk, and M. Paiva. Ventilation-perfusion matching in long-term microgravity. J. Appl. Physiol. 89: 2407-2412.
  38. Elliott, A.R., S.A. Shea, D-J. Dijk, J.K. Wyatt, E. Riel, D.F. Neri, C.A. Cziesler, J.B. West, and G.K. Prisk. Microgravity reduces sleep-disordered breathing in normal humans. Am. J. Respir. Crit. Care Med. 164: 478-485, 2001.
  39. Dijk, D-J, D.F. Neri, J.K. Wyatt, J.M. Ronda, E. Riel, A. Ritz-de Cecco, R.J. Hughes, A.R. Elliott, G.K. Prisk, J.B. West, and C.A. Czesiler. Sleep, performance, circadian rhythms, and light-dark cycles during two space shuttle flights. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 281: R1647-R1664, 2001.
  40. Prisk, G.K., S. Verhaeghe, D. Padeken, H. Hamacher, and M. Paiva. Three-dimensional ballistocardiography and respiratory motion in sustained microgravity. Aviat. Space and Envir. Med. 72: 1067-1074, 2001.
  41. Barash, I.A., C. Beatty, F.L. Powell, G.K. Prisk, and J.B. West. Nocturnal oxygen enrichment of room air at 3800 meter altitude improves sleep architecture. High Altitude Med and Biol. 2: 525-533, 2001.
  42. Prisk, G.K., J.M. Fine, A.R. Elliott, and J.B. West. Effect of 6-degree head-down tilt on cardiopulmonary function: Comparison with microgravity. Aviat. Space and Envir. Med. 73:8-16, 2002.
  43. Prisk, G.K., M.Paiva, and J.B. West (eds.) Gravity and the lung: Lessons from microgravity. New York, NY, Marcel Dekker, Inc., 2001.
  44. Mills, C.N., C. Darquenne, and G.K. Prisk. Mode shift of an inhaled aerosol bolus is correlated with flow sequencing in the human lung. J. Appl. Physiol. 92: 1232-1238, 2002.
  45. Prisk, G.K., J. Hammer, and C.J.L. Newth. Techniques for the measurement of thoracoabdominal asynchrony. Pediatr. Pulmon. 34: 462-674, 2002.
  46. Dutrieue, B., M. Paiva, S. Verbanck, M. LeGouic, C. Darquenne, and G.K. Prisk. Tidal volume single-breath washin of SF6 and CH4 in transient microgravity. J. Appl. Physiol. 94: 75-82, 2003.
  47. Migeotte, P-F., G.K. Prisk, and M. Paiva. Microgravity alters respiratory sinus arrhythmia and short-term heart rate variability in humans. Am. J. Physiol. Heart Circ. Physiol. 284: H1995-H2006, 2003.
  48. Darquenne, C. and G.K. Prisk. Effect of gravitational sedimentation on simulated aerosol dispersion in the human acinus. J. Aerosol Sci. 34: 405-418, 2003.
  49. Prisk, G.K., H.J.B. Guy, J.B. West, and J.W. Reed. Validation of measurements of ventilation-to-perfusion ratio inequality in the lung from expired gas. J. Appl. Physiol. 94: 1186-1192, 2003.
  50. Olfert, I.M. and G.K. Prisk. Effect of 60-degree head-down tilt on peripheral gas mixing in the human lung. J. Appl. Physiol. 97: 827-834, 2004.
  51. Darquenne, C. and G.K. Prisk. Aerosol deposition in the human respiratory tract breathing air and 80:20 heliox. J. Aerosol Med. 17:278-285, 2004.
  52. Darquenne, C. and G.K. Prisk. Effect of small flow reversals on aerosol mixing in the alveolar region of the human lung. J. Appl. Physiol. 97: 2083-2089, 2004.
  53. Thompson, B.R., G.K. Prisk, P. Peyton, R.J. Pierce, and P.D. Rochford. Inhomogeneity of ventilation leads to unpredictable errors in DLCO. Respir. Physiol. & Neurobiol. 146: 205-214, 2005.
  54. Darquenne, C., and G.K. Prisk. Aerosols in the study of convective acinar mixing. Respir. Physiol. & Neurobiol. 148: 207-216, 2005.
  55. Dutrieue, B., S. Verbanck, C. Darquenne, and G.K. Prisk. Airway closure in microgravity. Respir. Physiol. & Neurobiol. 148:97-111, 2005.
  56. Prisk, G.K., J.M. Fine, T.K. Cooper, and J.B. West. Pulmonary gas exchange is not impaired 24-hours following extra-vehicular activity. J. Appl. Physiol. 99: 2233-2238, 2005.
  57. Prisk, G.K. The lung in space. Clinics in Chest Medicine. 26: 415-438, 2005.
  58. Harrington, L., G.K. Prisk, C. Darquenne. Importance of the bifurcation zone and branch orientation in simulated aerosol deposition in the alveolar zone of the human lung. J. Aerosol Sci. 37: 37-62, 2005.
  59. Prisk, G.K. The respiratory system in space. Encyclopedia of Respiratory Medicine. G.J. Laurent and S.D. Shapiro (eds.), Elsevier, Oxford, UK. Vol 4, 113-119, 2006.
  60. Prisk, G.K., J.M Fine, T,K. Cooper and J,B. West. Vital Capacity, Respiratory Muscle Strength and Pulmonary Gas Exchange during Long-Duration Exposure to Microgravity. J. Appl. Physiol. 101: 439-447, 2006.
  61. Henderson, A.C., D.L. Levin, S.R. Hopkins, I.M. Olfert, R.B. Buxton, and G.K. Prisk. Steep head-down tilt has persisting effects on the distribution of pulmonary blood flow. J. Appl. Physiol. 101: 583-589, 2006.
  62. Hopkins, S.R., A.C. Henderson, D.L. Levin, K. Yamada, T, Arai, R.B. Buxton, and G.K. Prisk. Vertical gradients in regional lung density and perfusion in the supine human lung: The Slinky effect. J. Appl. Physiol. 103: 240-248, 2007.
  63. Kleinsasser, A.T., I.M. Olfert, A. Loeckinger, G.K. Prisk, S.R. Hopkins, and P.D. Wagner. Tidal volume dependency of gas exchange in bronchoconstricted pig lungs. J. Appl. Physiol. 103: 148-155, 2007.
  64. Jarvis, S.S., B.D. Levine, G.K. Prisk, B.E. Shykoff, A.R. Elliott, E. Rosow, C.G. Blomqvist, and J.A. Pawelczyk. Simultaneous determination of the accuracy and precision of closed-circuit cardiac output rebreathing techniques. J. Appl. Physiol. 103: 867-874, 2007.
  65. Prisk, G.K., K. Yamada, A.C. Henderson, T, Arai, D.L. Levin, R.B. Buxton, and S.R. Hopkins. Pulmonary perfusion in the prone and supine postures in the normal human lung. J. Appl. Physiol. 103: 883-894, 2007.
  66. Cnockaert, L., P.F. Migeotte, L. Daubigny, G.K. Prisk, F. Grenez, R.C. Sá.  A method for the analysis of respiratory sinus arrhythmia using continuous wavelet transforms.  IEEE Trans. Biomed. Eng. 55: 1640-1642, 2008
  67. Peterson, J.B., G.K. Prisk, and C.Darquenne.  Aerosol deposition in the human lung periphery is increased by reduced-density gas breathing. J. Aerosol Med. Pulm.Drug Delivery, 21: 159-168, 2008. DOI: 10.1089/jamp.2007.0651
  68. Prisk, G.K., Janelle M. Fine, Trevor K. Cooper and John B. West.  Lung function is unchanged in the 1G environment following 6-months exposure to microgravity.  Eur. J. Appl. Physiol., 103: 617-623, 2008.  DOI: 10.1007/s00421-008-0754-2
  69. Darquenne,C., and G.K. Prisk.  Deposition of inhaled particles in the human lung is more peripheral in lunar than in normal gravity.  Eur. J. Appl. Physiol., 10: 687-695, 2008.  DOI: 10.1007/s00421-008-0766-y
  70. Hopkins, S.R. and G. K. Prisk.  Point:Counterpoint: Gravity is/is not the major factor determining the distribution of blood flow in the human lung.  J. Appl. Physiol.  104: 1357-1358, 2008. DOI: 10.1152/japplphysiol.90402.2008.
  71. Arai, T.J., A.C. Henderson, D.J. Dubowitz, D.L. Levin, P.J. Friedman, R.B. Buxton, G.K. Prisk, and S.R. Hopkins.  Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans.  J. Appl. Physiol., 106: 1057-1064, 2008.  doi:10.1152/japplphysiol.90759.2008. PMCID: PMC Journal – In Process.
  72. Darquenne, C., L. Harrington, and G.K. Prisk.  Alveolar duct expansion greatly enhances aerosol deposition: A three-dimensional CFD study.  Phil. Trans. R. Soc. A, 367: 2333-2346, 2009.  doi:10.1098/rsta.2008.0295. PMCID: PMC Journal – In Process.
  73. Henderson, A.C., G.K. Prisk, D.L. Levin, S.R. Hopkins, and R.B. Buxton. Characterizing pulmonary blood flow distribution measured using arterial spin labeling. NMR in Biomed.  22:1025-1035, 2009.  PMCID: PMC Journal – In Process.
  74. Theilmann, R.J., T.J. Arai, A. Samiee, D.J. Dubowitz, S.R. Hopkins, R.B. Buxton, and G. K. Prisk. Quantitative MRI measurement of lung density must account for the change in T2* with lung inflation.  J. Mag. Reson. Imaging.  30: 527-534, 2009.  doi:10.1002/jmri.21866. PMCID: PMC Journal – In Process.
  75. Moore, G., S.C. Wong, C. Darquenne, T.S. Neuman, J.B. West, and G.K. Prisk.  Ventilation-perfusion inequality in the human lung is not increased following no-decompression-stop hyperbaric exposure.  Eur. J. Appl. Physiol., In Press, 2009.
  76. Burnham, K.J., T.J. Arai, D.J. Dubowitz, A.C. Henderson, S. Holverda, R.B. Buxton, G. K. Prisk, and S.R. Hopkins.  Pulmonary perfusion heterogeneity is increased by sustained heavy exercise in humans.  J. Appl. Physiol. 107 1559-1568 , 2009.  doi: 0: 00491.2009v1. PMCID: PMC Journal – In Process.
  77. Johnson, P.L., D.A. Popa, G.K. Prisk, C.E. Sullivan, N. Edwards. Non-invasive Positive Pressure Ventilation during Sleep at 3800m: relationship to Acute Mountain Sickness and sleeping oxyhemoglobin saturation.  Respirology.  15: 277-282, 2010. doi: 10.1111/j.1440-1843.2009.01678.x
  78. Sá, R.C., G.K. Prisk, and M. Paiva.  Microgravity alters respiratory abdominal and rib cage motion during sleep.  J. Appl. Physiol. 107: 1406-1412, 2009. doi:10.1152/japplphysiol.91516.2008.
  79. Prisk, G.K., I.M. Olfert, T.J. Arai, P.D. Wagner, and S.R. Hopkins.  Rapid intravenous infusion of 20ml/kg saline does not impair resting pulmonary gas exchange in the healthy human lung. J. Appl. Physiol. 108: 53-59 2009. doi:10.1152/japplphysiol.00787.2009, PMCID: PMC Journal – In Process.
  80. Hopkins S.R., and G.K. Prisk. Lung perfusion measured using magnetic resonance imaging: New tools for physiological insights into the pulmonary circulation J Magn Reson Imaging, 32: 1287-1301, 2010.  DOI 10.1002/jmri.22378
  81. Prisk, G.K.  Flow sensors for respiratory gases.  Biomedical Sensors. D.P. Jones (ed.).  Momentum Press, Highland Park, NJ.  pp 107-128, 2010.
  82. Prisk, G.K. Pulmonary circulation in extreme environments.  Comprehensive Physiology: Pulmonary Circulation. 1:319-338, 2011.   I.F. McMurtry, W.W. Wagner, Jr., T. Stevens, and M.N. Gillespie (eds.).  Wiley-Blackwell, Oxford, UK.
  83. Prisk, G.K.  Gas exchange under altered gravitational stress.  Comprehensive Physiology: Gas Exchange.  1: 339-355, 2011.  P.D. Wagner, and M.P. Hlastala (eds.).  Wiley-Blackwell, Oxford, UK.
  84. Prisk, G.K.  Microgravity.  Comprehensive Physiology: Respiration Mechanics: Organ, Cell, Molecule.  1: 485-497, 2011.  J.J. Fredberg, G.C. Sieck, and W.T. Gerthoffer (eds.).  Wiley-Blackwell, Oxford, UK.
  85. Hopkins, S.R., T.J. Arai, A.C. Henderson, D.L. Levin, R.B. Buxton, and G. K. Prisk. Lung volume does not alter the distribution of pulmonary perfusion in dependent lung in supine humans.  J. Physiol. (Lond.)  588.23: 4759-4768, 2010. DOI: 10.1113/jphysiol.2010.196063
  86. Sá, R-C., M.V. Cronin, A.C. Henderson, S. Holverda, R.J. Theilmann, T.J. Arai, D.J. Dubowitz, S.R. Hopkins, R.B. Buxton, and G.K. Prisk. Vertical distribution of specific ventilation in normal supine humans measured using oxygen-enhanced proton MRI.  J. Appl. Physiol., 109:1950-1959, 2010. doi:10.1152/japplphysiol.00220.2010
  87. Dummer, J.F., M.K. Storer, W-P. Hu, M.P. Swanney, G.J. Milne, C.M. Frampton, J.M. Scotter, G.K. Prisk and M.J. Epton. Accurate, reproducible measurement of acetone concentration in breath using selected ion flow tube-mass spectrometry.  J. Breath Res. 4: 046001, 2010. doi:10.1088/1752-7155/4/4/046001
  88. Holverda, S., R.J. Theilmann, R.C. Sá, T.J. Arai, E.T. Hall, D.J. Dubowitz, G.K. Prisk, and S.R. Hopkins. Measuring lung water: Ex vivo validation of multi-image gradient echo MRI.  J. Mag. Reson. Imaging, 34: 220-224, 2011. doi: 10.1002/jmri.22600.
  89. Darquenne, C., C. van Ertbruggen, and G.K. Prisk.  Convective flow dominates aerosol delivery to the lung segments. J. Appl. Physiol., 111:48-54, 2011. doi:10.1152/japplphysiol.00796.2010.
  90. Arai, T.J., Prisk, G.K., Holverda, S., Sá, R.C., Theilmann, R.J., Henderson, A.C., Cronin, M.V., Buxton, R.B., Hopkins, S.R., Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling. J. Vis. Exp. 51: 2011. doi: 10.3791/2712.
  91. DeRidder, S., P.-F. Migeotte, X. Neyt, N. Pattyn, and G. K. Prisk. Three-Dimensional Ballistocardiography in Microgravity: a Review of Past Research. Engineering in Medicine and Biology Society (EMBC), 2011 Annual International Conference of the IEEE: 4267-4270.  (Conference paper). DOI: 10.1109/IEMBS.2011.6091059.
  92. Migeotte, P.-F., J. Tank, N. Pattyn, I. Funtova, R. M. Baevsky, X Neyt, and G. K. Prisk. Three dimensional ballistocardiography: methodology and results from microgravity and dry immersion. Engineering in Medicine and Biology Society (EMBC), 2011 Annual International Conference of the IEEE: 4271-4274. (Conference Paper). DOI: 10.1109/IEMBS.2011.6091060
  93. Henderson, A.C., R.C. Sá, I.A. Barash, S. Holverda, R.B. Buxton, S.R. Hopkins, and G.K. Prisk. Rapid intravenous infusion of 20 mL/kg saline alters the distribution of perfusion in healthy supine humans. Resp. Physiol. And Neurobiol. 180: 331-341, 2012. doi:10.1016/j.resp.2011.12.013 PMC3273583
  94. Burrowes, K.S., R.B. Buxton, and G.K. Prisk. Assessing potential errors of MRI-based measurements of pulmonary blood flow using a detailed network flow model. J. Appl. Physiol. 113: 130-141, 2012. doi:10.1152/japplphysiol.00894.2011 PMC3404828
  95. Darquenne, C., R.C. Sá, G.K. Prisk. Cardiogenic mixing increases aerosol deposition in the human lung in the absence of gravity. Acta Astronautica. 92: 15-20, 2013. DOI: 10.1016/j.actaastro.2012.05.022
  96. Prisk, G.K., and H.T. Robertson. Editorial: Seeing may be believing. J. Appl. Physiol. 113: 315-316, 2012. DOI: 10.1152/japplphysiol.00527.2012
  97. Linnarsson, D., J. Carpenter, B. Fubini, P. Gerde, L.L. Karlsson, D.J. Loftus, G.K. Prisk, U. Staufer, E.M. Tranfield, and W. van Westrenen. Toxicity of lunar dust. Planetary and Space Sciences. 74: 57-71, 2012. DOI: 10.1016/j.pss.2012.05.023
  98. P-F. Migeotte, P-F., S. De Ridder, J. Tank, N. Pattyn, I. Funtova, R. Baevsky, X. Neyt, G.K. Prisk. Three dimensional ballisto- and seismo-cardiography: HIJ wave amplitudes are poorly correlated to maximal systolic force vector. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE: 5046-5049 (Conference Paper). DOI: 10.1109/EMBC.2012.6347127
  99. Asadi, A.K., M.V. Cronin, R.C. Sá, R.J. Theilmann, S. Holverda, S.R. Hopkins, R.B. Buxton, G.K. Prisk. Spatial-temporal dynamics of pulmonary blood flow in the healthy human lung in response to altered Fio2. J. Appl. Physiol., 114: 107-118, 2013. doi: 10.1152/japplphysiol.00433.2012 PMC3544514
  100. Darquenne, C. and G.K. Prisk. Particulate Deposition in the Human Lung Under Lunar Habitat Conditions. Aviat. Space and Envir. Med., 84: 190-195, 2013. DOI: 10.3357/ASEM.3387.2013
  101. Oakes, J.M., M. Scadeng, E. Breen, G.K. Prisk, and C. Darquenne. Regional distribution of aerosol distribution in rat lungs using magnetic resonance imaging. Ann. Biomed. Eng. 41: 967-978, 2013. DOI: 10.1007/s10439-013-0745-2
  102. van Loon, J.J.W.A., J.P. Baeyens, J. Berte, S. Blanc, L. Braak, K. Bok, J. Bos, R. Boyle, N. Bravenboer, E.M.W. Eekhoff, A. Chouker, G. Clement, P. Cras, E. Cross, M.A. Custaud, M. De Angelis, T. Delavaux, R. Delfos, C. Poelma, P. Denise, D. Felsenberg, K. Fong, C. Fuller, S. Grillner, E. Groen , J. Harlaar, M. Heer, N. Heglund, H. Hinghofer-Szalkay, N. Goswami, M. Hughes-Fulford, S. Iwase, J.M. Karemaker, B. Langdahl, D. Linnarsson, C. Lüthen, M. Monici, E. Mulder, M. Narici, P. Norsk, W. Paloski, G.K. Prisk, M. Rutten, P. Singer, D.F. Stegeman, A. Stephan, G.J.M. Stienen, P. Suedfeld, P. Tesch, O. Ullrich, R. van den Berg, P. Van de Heyning, A. Delahaye, J. Veyt , L. Vico, E. Woodward, L. Young, F. Wuyts. A Large Human Centrifuge for Exploration and Exploitation Research. Annales Kinesiologiae, 2012(1), 107-121.
  103. Henderson, A.C, R.C. Sá, R.J. Theilmann, R.B. Buxton, G.K. Prisk, S.R. Hopkins. The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung. J.Appl.Physiol. 115: 313-324, 2013. doi: 10.1152/japplphysiol.01531.2012
  104. Tedjasaputra, V., R.C. Sá, T.J. Arai, S. Holverda, R.J. Theilmann, W.T. Chen, P.D. Wagner, C.K. Davis, G.K. Prisk, and S.R. Hopkins. The heterogeneity of regional specific ventilation is unchanged following heavy exercise in athletes. J.Appl.Physiol. 115: 126-135, 2013. doi: 10.1152/japplphysiol.00778.2012
  105. Darquenne, C., K.L. Zeman, R.C. Sá, T.K. Cooper, J.M. Fine, W.D. Bennett, and G.K. Prisk. Removal of sedimentation decreases relative deposition of coarse particles in the lung periphery. J. Appl. Physiol. 115: 546-555, 2013. doi:10.1152/japplphysiol.01520.2012
  106. Prisk, G.K., and S.R. Hopkins. Pulmonary Gas Exchange. Colloquium Series on Integrated Systems Physiology: From Molecule to Function, August 2013, 86 pages, Morgan and Claypool Life Sciences. doi:10.4199/C00087ED1V01Y201308ISP041
  107. Prisk, G.K. and P-F. Migeotte. Physiological insights from gravity-free ballistocardiography. Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE: 7282-7285 (Conference Paper). DOI: 10.1109/EMBC.2013.6611239
  108. Hall, E.T., R.C. Sá, S. Holverda, T.J. Arai, D.J. Dubowitz, R.J. Theilmann, G.K. Prisk. and S.R. Hopkins. The effect of supine exercise on the distribution of regional pulmonary blood flow measured using proton MRI. J. Appl. Physiol. In Press, 2013.
  109. Prisk, G.K., and R.C. Sá. It’s about numbers, not pictures. J. Appl. Physiol. 116: 127-128, 2014. doi:10.1152/japplphysiol.01348.2013 (Editorial)
  110. Prisk, G.K., Microgravity and the respiratory system. Eur. Respir. J. In Press, 2014. (Invited Review).
  111. Sá, R.C., A.K. Asadi, R.J. Theilmann, S.R. Hopkins, G.K. Prisk, and C. Darquenne. Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging. J. Appl. Physiol. In Press, 2014.